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SPRAVATO® is an FDA‑approved nasal spray derived from ketamine and used in combination with an oral antidepressant. Unlike daily medications that work gradually, SPRAVATO® targets the brain’s glutamate system, which plays a key role in mood, learning, and neuroplasticity.
Many patients report:
Rapid improvement in depressive symptoms
Relief from emotional numbness or hopelessness
Improved ability to engage in therapy and daily life
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SPRAVATO® helps the brain form new neural connections, which may restore communication between areas involved in mood regulation.
During treatment:
The medication is self‑administered under medical supervision
Sessions last about 2 hours for monitoring
Temporary effects such as dissociation, dizziness, or sleepiness may occur
Between treatments:
Patients often notice improved mood, clarity, and emotional flexibility
Benefits may build over time with a structured treatment plan
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Comprehensive Evaluation
A Journey Psychiatry provider will determine if SPRAVATO® is appropriate for you.Treatment Sessions
Administered in‑office only
Comfortable, calm setting
Continuous monitoring by trained clinical staff
Post‑Treatment Care
You’ll need a ride home after each session
Ongoing medication management and therapy coordination
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SPRAVATO® may be an option for you if:
You’ve tried two or more antidepressant medications without adequate relief
You continue to experience persistent or severe depressive symptoms
You are a new patient seeking advanced treatment options or an existing patient who hasn’t responded well to current medications
If you’re an existing Journey Psychiatry patient and feel that your current treatment isn’t working, simply let your provider know you’d like to discuss SPRAVATO® as a potential next step.
A full evaluation is required to determine eligibility and ensure this treatment is appropriate for you.
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SPRAVATO® is only available through the FDA’s REMS program to ensure safety.
At Journey Psychiatry, we prioritize:
Medical oversight by psychiatric providers
Blood pressure and symptom monitoring
Trauma‑informed, patient‑centered care
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Many insurance plans cover SPRAVATO® for approved indications.
Our team will:
Verify benefits
Assist with prior authorizations
Discuss out‑of‑pocket costs upfront
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Journey Psychiatry is unique in our team-based, collaborative approach to SPRAVATO® treatment.
What sets us apart:
Experienced psychiatric providers and dedicated SPRAVATO® clinical staff
Our private SPRAVATO® treatment rooms are intentionally designed to enhance comfort, privacy, and emotional safety—supporting a more meaningful and restorative experience.
Optional SPRAVATO® therapy sessions offered in conjunction with treatment
By combining medication treatment with guided therapeutic (counseling) support, we help patients:
Process their experience safely
With coordinated therapy, patients are often able to connect more deeply with their emotions & experiences, creating space for insight, healing, and lasting change.
Feel supported by a coordinated care team
This integrated approach is designed to optimize outcomes and support long-term healing—not just symptom relief.
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If depression has felt overwhelming or resistant to treatment, SPRAVATO® may offer a new path forward.
New patients: Reach out to schedule an evaluation with our team
Existing patients: Let your provider know you’d like to explore SPRAVATO® as an option
You’re also welcome to contact our SPRAVATO® Coordinator, who can guide you through the process, answer questions, and help you feel confident about next steps.
📞 Call us or request an appointment today to begin a hopeful, supported journey toward healing.
SPRAVATO® (Esketamine) Treatment
A New Option for Treatment-Resistant Depression
At Journey Psychiatry & Behavioral Health, proudly serving Trinity and the greater Tampa Bay area, we offer SPRAVATO® (esketamine) nasal spray for adults struggling with depression that hasn’t improved with traditional treatments.
If you’re feeling stuck, exhausted, or discouraged after trying multiple antidepressants, you’re not alone, and there are new options. SPRAVATO® offers a different approach and renewed hope for many patients.
This treatment is available for both new and existing patients following a comprehensive evaluation.
SPRAVATO® is a registered trademark of Janssen Pharmaceuticals. This page is for informational purposes only and does not replace medical advice.